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Updated: Apr 13, 2026

Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface
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Adhesion Frequency Assay for In Situ Kinetics Analysis of Cross-Junctional Molecular Interactions at the Cell-Cell Interface

Published on: November 2, 2011

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直接观察涉及细胞粘附分子的捕获键

Bryan T Marshall1, Mian Long, James W Piper

  • 1Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30332, USA.

Nature
|May 9, 2003
PubMed
概括

这项研究揭示了selectin-ligand键在机械力下表现出捕捉和滑动行为,影响白细胞滚动动态. 这种力量依赖的双重反应对于在不同的机械应力环境中调节细胞粘附至关重要.

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Adhesion01:14

Adhesion

Adhesion occurs when one type of molecule is attracted to a different molecule. Water exhibits adhesive properties in the presence of polar surfaces, such as glass or cellulose in plants. For instance, when water is poured into a glass, the positively charged hydrogen molecules of water are more attracted to the negatively charged oxygen molecules in the silica than to the oxygen in neighboring water molecules.
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