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Updated: Jul 5, 2026

Measuring G-protein-coupled Receptor Signaling via Radio-labeled GTP Binding
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对小GTPase Rab6的重组抗体作为形状传感器

Clement Nizak1, Solange Monier, Elaine del Nery

  • 1CNRS UMR144, Institut Curie, 26 rue d'Ulm, F75248 Paris Cedex 05, France.

Science (New York, N.Y.)
|May 10, 2003
PubMed
概括

研究人员使用抗体菌体显示器开发了分子构成传感器,以跟踪瓜诺辛三酸酶 (GTPase) Rab6. 这种方法可视化了细胞中的Rab6-GTP,并揭示了它在调节运输中间体中的作用,为研究分子动力学提供了新的工具.

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