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Updated: Jul 8, 2026

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins
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通过改进的核糖体,增强D-氨基酸的融入蛋白质

Larisa M Dedkova1, Nour Eddine Fahmi, Serguei Y Golovine

  • 1Departments of Chemistry and Biology, University of Virginia, Charlottesville, VA 22904, USA.

Journal of the American Chemical Society
|May 29, 2003
PubMed
概括

经过修改的大肠杆菌核糖体使得D-氨基酸能够更好地被纳入蛋白质中. 一些由此产生的蛋白质,如二叶酸还原酶,保留了充分的功能,证明了新型蛋白质工程的潜力.

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