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相关概念视频

Pulse rhythm01:30

Pulse rhythm

Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
Electrophysiology of Normal Cardiac Rhythm01:19

Electrophysiology of Normal Cardiac Rhythm

The normal cardiac rhythm is a synchronized electrical activity that facilitates the regular and coordinated contraction of the heart muscle. This process is essential for efficient blood circulation throughout the body. The fundamental elements involved in establishing and maintaining this rhythm include the unique electrical properties of cardiac muscle cells, the sinoatrial (SA) node's pacemaker function, the specialized conducting system, and the ionic mechanisms underlying each phase of...
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
Dysrhythmias V: Evaluating Dysrhythmias01:30

Dysrhythmias V: Evaluating Dysrhythmias

Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
Dysrhythmias VI: Management of Dysrhythmias01:25

Dysrhythmias VI: Management of Dysrhythmias

Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...

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相关实验视频

Updated: Jul 9, 2026

Programmed Electrical Stimulation in Mice
07:29

Programmed Electrical Stimulation in Mice

Published on: May 26, 2010

腹腔节拍对心力衰竭和心房的不良影响,在患者中具有正常的基线QRS持续时间,在一个临床试验中,用于治疗鼻节功能障碍的起器治疗.

Michael O Sweeney1, Anne S Hellkamp, Kenneth A Ellenbogen

  • 1Cardiac Arrhythmia Service, Brigham and Women's Hospital and Harvard Medical School, 75 Francis St, Boston, Mass 02115, USA. mosweeney@partners.org

Circulation
|June 5, 2003
PubMed
概括

室腔脱同步从节奏,即使保留AV同步,提高心力衰竭和心房动的风险在鼻节功能障碍患者与正常的基线QRS持续时间. 这强调了尽量减少心室节奏的重要性.

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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
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科学领域:

  • 心脏病学 心脏病学
  • 电子生理学 电子生理学
  • 医疗器械技术 医疗器械技术

背景情况:

  • 双室 (DDDR) 节奏保持心房 (AV) 同步,可能减少心力衰竭 (HF) 和心房动 (AF) 在鼻节功能障碍 (SND).
  • 然而,由于右心室刺激,DDR节奏可以延长QRS持续时间 (QRSd),导致心室脱同步.
  • 节奏诱导的腹腔失同对基线QRSd正常的患者的影响尚不清楚.

研究的目的:

  • 为了研究由节奏诱导的心室脱同步对心力衰竭住院和心房的风险的影响,在患有鼻节功能障碍和正常基线QRS持续时间的患者中.

主要方法:

  • 从MOST试验 (2010年患者,6年) 的数据分析,比较SND中的DDR和心室 (VVIR) 节奏.
  • 在心脏起器植入之前,通过心电图测量了基线QRSd.
  • 累积百分比心室节奏 (Cum%VP) 根据心脏起器数据确定; 考克斯模型评估了Cum%VP对HF住院和AF的时间依赖效应.

主要成果:

  • 在基线QRSd<120毫秒的患者中,Cum%VP在DDDR组 (90%) 与VVIR组 (58%) 相比显著更高.
  • 在两个节奏组中,增加的Cum%VP是HF住院的强有力的预测因素 (DDDR:HR 2.99>40%VP;VVIR:HR 2.56>80%VP).
  • 在两组中,AF风险与Cum%VP线性增加,每增加25%的腹腔动脉节奏就观察到显著的关联.

结论:

  • 心室脱同,即使心房心房同步是通过DDR节奏保持,增加了心力衰竭住院治疗和心房的风险.
  • 这些发现表明,最小化心室节奏对于SND患者和正常基线QRSd患者至关重要,以减轻不良心血管结果.