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Updated: Jul 8, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Published on: October 26, 2015

同一个激素在同类受体上具有不同的结合方向:锁和钥匙还是简单的?

Ting-Wei Mu1, Henry A Lester, Dennis A Dougherty

  • 1Division of Chemistry and Chemical Engineering and Division of Biology, California Institute of Technology, Pasadena, California 91125, USA.

Journal of the American Chemical Society
|June 5, 2003
PubMed
概括

研究人员研究了C. elegans中的血清素受体MOD-1. 他们发现它使用的是与5-HT3受体不同的托芬残留物,这表明在结合时发生了连接体重组.

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