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基于瓜尼丁的核酸 (GPNA) 的新型结合和有效的细胞吸收

Peng Zhou1, Miaomiao Wang, Lei Du

  • 1Department of Chemistry and Center for Light Microscope Imaging and Biotechnology, Carnegie Mellon University, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15253, USA.

Journal of the American Chemical Society
|June 5, 2003
PubMed
概括

有关关瓜尼丁组的修改型核酸 (PNA) 在哺乳动物细胞中显示出高效的细胞吸收. 这些PNAs将DNA与沃森-克里克规则结合在一起,形成稳定的1:1复合体,与之前的2:1复合体不同.

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