相关实验视频
Updated: Jul 11, 2026
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Cerenkov Luminescence Imaging of Interscapular Brown Adipose Tissue
Published on: October 7, 2014
在环境温度下对光表面的成像结构水和结合的多糖化合物进行成像
Chiara Spagnoli1, Katja Loos, Abraham Ulman
1Othmer Department of Chemical and Biological Sciences and Engineering, Polytechnic University, Six Metrotech Center, Brooklyn, New York 11201, USA.
Journal of the American Chemical Society
|June 5, 2003
概括
一个有序的,类似冰的水单层在肌岩表面形成. 这种结构化的水层以原子力显微镜为特征,对像色素这样的生物样本的成像具有重要意义.
科学领域:
- 表面科学是一门科学.
- 材料科学是一种材料科学.
- 生物物理学的生物物理.
背景情况:
- 在环境条件下,在肌岩表面上存在一个有序的水层.
- 这层表现出类似冰的特性,并且可能是铁电,在表层与上对齐.
研究的目的:
- 为了描绘和描述表面上有序的水层.
- 为了研究湿和脱湿对水层结构的影响.
- 讨论对成像生物样本的影响.
主要方法:
- 使用了触摸模式原子力显微镜 (AFM).
- 进行了高度和接触角度测量.
- 在各种水化状态下分析了湿化和脱水过程.
主要成果:
- 顺序的水层被成功成像和表征.
- 确定了这些层的高度和接触角度.
- 该研究提供了关于水层形成和的行为数据.
结论:
- 在上有序水层的存在得到证实和特征.
- 这些发现对于理解表面水分和其对成像的影响很重要.
- 这项研究强调了对生物分子 (如色素) 的成像的潜在影响.
相关概念视频
01:18Imaging Biological Samples with Optical Microscopy
Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
In optical microscopy, the specimen to be viewed is placed on a glass slide and clipped on the stage...
01:20Preparation of Samples for Electron Microscopy
To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...