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Updated: Jul 11, 2026

Formation of Covalent DNA Adducts by Enzymatically Activated Carcinogens and Drugs In Vitro and Their Determination by 32P-postlabeling
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动态同位素效应涉及两个电友性氧化剂在细胞染色体p450催化氧化中

Martin Newcomb1, David Aebisher, Runnan Shen

  • 1Department of Chemistry, University of Illinois at Chicago, 60607, USA. men@uic.edu

Journal of the American Chemical Society
|June 6, 2003
PubMed
概括

在研究P450 (P450) 酶时,这项研究使用了动态同位素效应来揭示多个基化途径. 这些发现支持"两氧化剂"模型,而不是P450催化剂的"两状态"模型.

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