相关实验视频

Updated: Jul 6, 2026

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
13:10

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

通过ATRIP识别RPA-ssDNA复合体来检测DNA损伤

Lee Zou1, Stephen J Elledge

  • 1Verna & Marrs McLean Department of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA.

Science (New York, N.Y.)
|June 7, 2003
PubMed
概括

复制蛋白A (RPA) 对于招募ATR-ATRIP复合体到DNA损伤部位至关重要,从而启动关键的细胞检查点信号通路. 这一发现突出了RPA的重要性.

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