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Updated: Jul 7, 2026

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通过MHCII类细胞质域发送信号是抗原呈现所必需的,并诱导B7表达

N Nabavi1, G J Freeman, A Gault

  • 1Department of Immunopharmacology, Roche Research Center, Nutley, New Jersey 07110.

Nature
|November 19, 1992
PubMed
概括

截断的II类主要基因相容性复合体 (MHC) 分子通过影响B7分子诱导,损害B细胞抗原呈现. 恢复信号通路,就像循环AMP一样,可以扭转这种缺陷.

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