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Biaxial Mechanical Characterizations of Atrioventricular Heart Valves
Published on: April 9, 2019
前额头肌叶片的移动性受到基本停留和弦的限制
Wolfgang A Goetz1, Hou-Sen Lim, Filip Pekar
1The International Heart Institute of Montana Foundation at St Patrick Hospital and Health Sciences Center and University of Montana, 554 W Broadway, Missoula, Mont 59802, USA.
Circulation
|June 11, 2003
概括
前基底停留和弦限制前额头肌叶片运动. 切断这些和弦增加了叶片的运动,这表明它在透缩左心室填充和缩外流中发挥了作用.
科学领域:
- 心血管解剖学 心血管解剖学
- 心脏生物力学心脏生物力学
- 中心门生理学 中心门生理学
背景情况:
- 前基底停留和弦被假设在整个心脏循环中限制前额叶叶片运动.
- 这些结构被认为在左心室内调节血液流动动力学方面发挥作用.
研究的目的:
- 为了研究前基底停留和弦对前额叶叶片 (AL) 运动的机械影响.
- 量化停留和弦切割对心脏周期期间AL动态的影响.
主要方法:
- 在绵羊体内植入声微米晶体,以测量关键点之间的距离,包括AL, mitra annulus,和停留和弦插入 (S1,S2).
- 测量记录了手术切割前面的基底停留和弦之前和之后的测量.
- 在整个心脏周期中,分析了AL和相关结构的角度和线性移位.
主要成果:
- 前额头叶片 (AL) 在心脏循环期间表现出显著的角度运动,在S1和S2观察到的特定变化.
- 在透析过程中,AL跨越了E和A波期间停留和弦形成的平面.
- 切断停留弦导致AL的横向运动显著增加 (P<0.05).
结论:
- 虽然停留和弦限制了横向AL运动,但中间部分在它们之间自由移动,在透气时起着帆船般的作用.
- 这种机制有助于扩张性左心室输入和收缩性输出道.
- 在停留弦切割后观察到增加横向AL运动,突出显示了它们的限制性作用.
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