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Updated: Jul 5, 2026

Determination of the Gas-phase Acidities of Oligopeptides
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Determination of the Gas-phase Acidities of Oligopeptides

Published on: June 24, 2013

混合QM/MM研究转酸化反应中的效应

Brent A Gregersen1, Xabier Lopez, Darrin M York

  • 1Department of Chemistry, University of Minnesota, 207 Pleasant Street SE, Minneapolis, Minnesota 55455, USA.

Journal of the American Chemical Society
|June 12, 2003
PubMed
概括

混合量子/分子力学模拟揭示了酸-酸转化中的thio效应. 替代影响反应障碍和速度限制步骤,为RNA催化机制提供了洞察力.

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Reaction Quotient02:35

Reaction Quotient

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Free Energy Changes for Nonstandard States03:25

Free Energy Changes for Nonstandard States

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Leveling Effect and Non-Aqueous Acid-Base Solutions

This lesson defines the leveling effect in acidic and basic solutions and its role in aqueous and non-aqueous solutions. It is essential to understand the competing nature of various species in a chemical system.
The Leveling Effect of a Solvent
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Reactions of Acid Anhydrides

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Substituent Effects on Acidity of Carboxylic Acids

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Composition of Polyprotic Acid Solutions as a Function of pH

Polyprotic acids of the type H2M constitute two ionizable protons. As a result, on titration with a base, they exhibit two equivalence points in the titration curve. During titration, the species H2M, HM−, and M2− will be present in the solution at different points. The fractions of H2M, HM−, and M2− present at the various instances of the titration are denoted by α0, α1, and α2, respectively.
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