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Atomic Scale Structural Studies of Macromolecular Assemblies by Solid-state Nuclear Magnetic Resonance Spectroscopy
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伴随核酸间反应的水合变化:体积特征

Feixue Han1, Tigran V Chalikian

  • 1Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, 19 Russell Street, Toronto, Ontario M5S 2S2, Canada.

Journal of the American Chemical Society
|June 12, 2003
PubMed
概括

乙与DNA和RNA等核酸结构的结合导致体积和可压缩性变化. 这些发现凸显了水合在药物与核酸相互作用中的关键作用.

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