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Nucleocapsid Annealing-Mediated Electrophoresis (NAME) Assay Allows the Rapid Identification of HIV-1 Nucleocapsid Inhibitors
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由HIV-1逆转录酶催化的DNA链转移反应的机制

J A Peliska1, S J Benkovic

  • 1Department of Chemistry, Pennsylvania State University, University Park 16802.

Science (New York, N.Y.)
|November 13, 1992
PubMed
概括

人类免疫缺陷病毒1逆转录酶 (HIV-1 RT) 催化DNA链转移,对逆转录病毒复制至关重要. 它的聚合酶活性可能导致基因错误融合,可能导致HIV-1基因组的超变性.

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