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相关概念视频

Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...

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A Recovery Cardiopulmonary Bypass Model Without Transfusion or Inotropic Agents in Rats
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使用可植入式心脏转换器-除器电图确定脆弱性的上限.

Charles Swerdlow1, Kalyanam Shivkumar, Jianxin Zhang

  • 1Cedars-Sinai Medical Center, Los Angeles, Calif, USA. swerdlow@ucla.edu

Circulation
|June 18, 2003
PubMed
概括

冲击电图的恢复时间 (TR) 准确地估计了接收可植入心脏转换器-除器 (ICD) 的患者的脆弱性上限 (ULV). 这一发现允许通过与TR相对计时T波冲击来自动确定ULV.

科学领域:

  • 心脏病学 心脏病学
  • 生物医学工程 生物医学工程
  • 电子生理学 电子生理学

背景情况:

  • 脆弱性的上限 (ULV) 对于在可植入心脏转换器-除器 (ICD) 中确定除门至关重要.
  • 识别ULV最脆弱的间隔需要分析ICD电图,而不仅仅是表面T波.
  • 假设T波的最大导数 (dV/dt) 的恢复时间 (TR) 与这些脆弱间隔相关.

研究的目的:

  • 调查T波恢复时间 (TR) 与除最脆弱的间隔之间的相关性.
  • 评估使用电图数据在ICD中自动化ULV确定的可行性.
  • 为了将TR与最新的T波峰值 (T峰值) 进行比较,用于定时除冲击.

主要方法:

  • 在ICD植入过程中,在25名患者中确定ULV,除门和脆弱间隔.
  • 通过计算T波的最大导数 (dV/dt) 来从冲击电图中测量TR.
  • 与TR与Tpeak相关联,并分析了与TR和Tpeak相对脆弱区间的时间.

主要成果:

  • TR与Tpeak的相关性很高 (Tpeak-TR = -2 ± 11 ms; rho = 0.80,P < 0.001).TR与Tpeak的相关性很高.
  • 在所有患者中,相对于Tpeak,最脆弱的间隔被确定在-20ms到+20ms之间.

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  • 大约96%的脆弱间隔发生在相对于TR的-40ms和+20ms之间.

    • 结论:

    • 来自冲击电图的T波恢复时间 (TR) 准确地反映了全球再极化.
    • TR作为Tpeak的可靠替代品,可以准确地定时除.
    • 在ICD中自动确定ULV是可以通过同步T波冲击与TR来实现的.