过去,现在和未来的方向来定义抑郁症最佳治疗结果:缓解和超越
1Department of Psychiatry and Human Behavior, Brown University School of Medicine, Providence, RI 02906, USA. martin_keller@brown.edu
JAMA
|June 19, 2003
概括
缓解是情绪障碍的最佳治疗结果,但目前的评估依赖于症状. 未来的神经科学的进步可能会使得更准确的,基于生物学的评估能够实现无疾病状态.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 情绪障碍 研究 研究 情绪障碍
背景情况:
- 缓解被认为是情绪障碍的最佳治疗结果.
- 目前的缓解指标缺乏一致的特征,导致评估变化.
- 现有的诊断和评估系统主要依赖于描述性症状和心理社会功能.
研究的目的:
- 突出需要在情绪障碍治疗中改进缓解标准的需要.
- 探索神经科学进步在改善情绪障碍评估方面的潜力.
- 讨论向更具生物学信息的诊断和评估系统的过渡.
主要方法:
- 关于情绪障碍治疗结果当前研究的综述.
- 对基于症状的缓解评估局限性的分析.
- 探索神经科学在临床实践中的潜在应用.
主要成果:
- 在定义和评估情绪障碍的缓解方面存在显著的变化.
- 神经科学为更客观地衡量疾病状态和治疗反应提供了潜力.
- 向神经生物学理解的转变可能会导致更精确的治疗策略.
结论:
- 虽然神经科学正在进步,但缓解评估目前依赖于临床症状和功能状态.
- 神经科学的未来发展可能会使更准确的,疾病特异性的评估成为可能.
- 最终的目标是为患有情绪障碍的患者实现真正的无疾病状态.
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