与TNF相关的诱导亡联体 (TRAIL) 作为在多发性硬化症中干扰素β治疗的潜在响应标志物

Klaus-Peter Wandinger1, Jan D Lünemann, Oliver Wengert

  • 1Institute of Neuroimmunology, Charité University Hospital, Schumannstrasse 20/21, 10117, Berlin, Germany.

PubMed
概括

与瘤坏死因子 (TNF) 相关的诱导亡的连接体 (TRAIL) 显示了对干扰素β反应的多发性硬化症患者的早期和持续诱导. 治疗前的TRAIL水平可以预测反应,有助于个性化治疗选择.

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