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Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors
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甘酸酸氨基醇对组织因子通路抑制剂的定

Jing Zhang1, Orlando Piro, Lan Lu

  • 1Division of Hematology, Barnes-Jewish Hospital at Washington University Medical Center, St Louis, Mo, USA.

Circulation
|July 2, 2003
PubMed
概括

组织因子通路抑制剂 (TFPI) 在内皮细胞上通过甘氨酸酸氨基醇 (GPI) 和其他蛋白质进行定. 这种膜结合对于局部调节凝血至关重要.

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