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蛋白质-DNA复合体的Allosteric抑制通过聚胺-插曲器结合物

Eric J Fechter1, Peter B Dervan

  • 1Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California 91125, USA.

Journal of the American Chemical Society
|July 10, 2003
PubMed
概括

新的头聚胺-氨酸结合物通过阻断蛋白质-DNA相互作用来抑制基因转录. 这些分子特别结合DNA,改变其结构以防止转录因子结合.

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