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在小鼠中通过转录因子Foxo3a抑制卵巢卵泡激活

Diego H Castrillon1, Lili Miao, Ramya Kollipara

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, and Department of Medicine, Harvard Medical School, Boston, MA 02115, USA.

Science (New York, N.Y.)
|July 12, 2003
PubMed
概括

雌性小鼠的Foxo3a缺乏导致卵巢卵泡激活,导致不孕. 这表明Foxo3a抑制早期的卵泡生长,其损失可能导致过早的卵巢衰竭.

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