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Quantitative Autonomic Testing
Published on: July 19, 2011
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血压和心率波动之间的相位转移的可变性:短期循环控制的标志物
Josef Halámek1, Tomás Kára, Pavel Jurák
1Institute of Scientific Instruments, Academy of Sciences, Královopolská 147, 612 64 Brno, Czech Republic. josef@isibrno.cz
Circulation
|July 16, 2003
概括
控制0.10赫兹的呼吸显示出血压和心率相互作用的差异. 这些发现,特别是在心脏转换器-除器接受者中,可能有助于突然心脏死亡的风险分层.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统功能自主神经系统功能
- 医学诊断 医学诊断 医学诊断
背景情况:
- 自主循环控制对心血管健康至关重要.
- 血压和心率波动的变化可能表明自主功能障碍.
- 0.10 Hz的频率被探索为评估这些波动的潜力.
研究的目的:
- 为了研究血压和心率波动之间的相位转移变异性在0.10Hz附近的有用性,以评估自主循环控制.
- 通过这些测量来区分健康人与患有心血管疾病的患者.
- 确定最佳的受控呼吸频率,以揭示这些差异.
主要方法:
- 研究了四组受试者:健康的年轻人,健康的老年人,冠状动脉疾病患者和心动除器 (ICD) 接受者.
- 在自由呼吸和控制呼吸时收集数据,频率为0.10 Hz和0.33 Hz.
- 分析的重点是相位转移和巴罗反射灵敏度的变化.
主要成果:
- 在ICD接受者和所有其他组之间观察到相变性的显著差异 (P<0.001).
- 在0.10赫兹时,显著差异 (P<0.01) 在巴罗反射灵敏度是显而易见的,与0.33赫兹不同.
- 年轻和老年健康个体在巴罗反射增加方面有所不同,但不是相变性.
结论:
- 控制0.10 Hz的呼吸频率有效地识别了血压与RR的相互作用.
- 这些相互作用,通过相变性和巴罗反射灵敏度来衡量,在有突发心律失常死亡风险的患者中显著改变.
- 这些短期循环控制测量可以改善心脏突然死亡风险分层.
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