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人类细胞染色体P450 2C9的晶体结构与华法林结合在一起

Pamela A Williams1, Jose Cosme, Alison Ward

  • 1Astex Technology, 436 Cambridge Science Park, Milton Road, Cambridge CB4 0QA, UK.

Nature
|July 16, 2003
PubMed
概括

人类CYP2C9的晶体结构揭示了它如何与药物华法林相互作用,揭示了一个新的结合口袋. 这一发现为药物代谢和潜在的药物相互作用提供了洞察力.

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