非霍奇金淋巴瘤非霍奇金淋巴瘤
Linda S Evans1, Barry W Hancock
1Weston Park Hospital, S10 2SJ, Sheffield, UK.
Lancet (London, England)
|July 18, 2003
概括
非霍奇金淋巴瘤包括各种恶性疾病. 分子生物学,分类和化疗和单克隆抗体等治疗方法的进步正在改善成年淋巴瘤的预后.
科学领域:
- 在瘤学瘤学.
- 血液学 血液学 血液学
- 分子生物学分子生物学
背景情况:
- 非霍奇金淋巴瘤是一种广泛的术语,用于具有各种临床和组织学特征的淋巴增殖性恶性疾病.
- 诊断可能具有挑战性,大约25%的病例呈现于外节,造成独特的临床问题.
研究的目的:
- 探索成年淋巴瘤的分子基础.
- 讨论通过生物学理解来制定一个分类系统的发展.
- 检查精细的预后因素分组是如何帮助临床管理的.
主要方法:
- 审查淋巴瘤亚型的分子基础.
- 分析不断发展的分类系统.
- 在临床决策中评估预后因素.
主要成果:
- 了解分子基础已经导致改善了淋巴瘤亚组的分类.
- 精细的预后因素识别提高了临床管理策略.
- 化疗改善了侵略性淋巴瘤的存活率;新型疗法对惰和侵略性类型有希望.
结论:
- 基于生物学的分类系统对于管理成年淋巴瘤至关重要.
- 化疗和单克隆抗体治疗的进步正在改善患者的治疗结果.
- 对分子机制和新治疗方法的持续研究将进一步改善淋巴瘤的预后.
相关概念视频
Lymphoid Cells and Tissues
Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...
Primary Lymphoid Organs
Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Secondary Lymphoid Organs
Secondary organs, including lymph nodes, the spleen, and mucosa-associated lymphoid tissue (MALT), work harmoniously to protect us from disease and infection.
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...
The spleen is a vital organ in the lymphatic system, nestled in the upper left side of the abdomen. It is composed of two primary regions: the red pulp and the white pulp, each having distinct functions. The red pulp performs a significant role in blood filtration. It efficiently purges the blood of old or damaged red blood cells and...


