基因切换由代谢酶 - - 你是如何进入邀请名单的?
1Department of Biochemistry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA.
Cell
|July 31, 2003
概括
在哺乳动物中,Oct-1转录因子和OCA-S复合体控制着基因表达. 糖-3-酸脱酶 (GADPH) 对于OCA-S功能来说非常重要,它增加了对基因组基因转录的氧化还原依赖性.
科学领域:
- 分子生物学分子生物学
- 基因规则 基因规则
- 生物化学 生物化学
背景情况:
- 基因表达对哺乳动物细胞的DNA复制和修复至关重要.
- 已知Oct-1转录因子及其同活性剂OCA-S复合体是基因组基因转录的调节者.
- 控制OCA-S复合体及其调节的精确分子机制仍然不完全理解.
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