通过减少多种主要风险因素来估计全球和区域潜在的健康益处
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Updated: Jul 21, 2026

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Published on: July 29, 2020
Majid Ezzati1, Stephen Vander Hoorn, Anthony Rodgers
1Risk, Resources, and Environmental Management Division, Resources for the Future, Washington, DC, USA. mezzati@hsph.harvard.edu <mezzati@hsph.harvard.edu>
Lancet (London, England)
|August 2, 2003
概括
在全球范围内解决主要风险因素可以显著提高健康的预期寿命. 同时的干预可以防止大量的疾病负担,并减少全球的健康差异.
科学领域:
- 全球健康 全球健康
- 流行病学 流行病学
- 预防医学 预防医学
背景情况:
- 估计多种风险因素带来的疾病负担对于评估联合预防策略至关重要.
- 很少有全球范围的调查量化了多种风险因素对疾病负担的影响.
研究的目的:
- 估计在全球范围内消除多个主要风险因素所带来的潜在健康益处.
- 量化疾病负担归因于全球不同地区主要风险因素的联合影响.
主要方法:
- 评估了14个全球流行病学子区域中与20个主要风险因素相关的疾病和伤害负担.
- 使用风险因子流行率和危险数据估计的人口归因分数 (PAF),考虑中介风险.
- 根据不同疾病的年龄和性别计算多种风险因素的关节PAF.
主要成果:
- 2000年,考虑的风险因素的联合影响占全球47%的过早死亡和39%的总疾病负担.
- 这些风险与大量主要疾病有关,包括腹 (92%-94%),缺血性心脏病 (83%-89%) 和中风 (70%-76%).
- 消除这些风险可以使全球的健康预期寿命增加9.3年 (17%),不同地区的差异.
结论:
- 消除主要风险因素为全球疾病预防和健康增长提供了巨大的潜力.
- 对主要风险的同时干预可以在所有地区增加健康的预期寿命.
- 解决这些风险可以帮助减少全球不同地区之间的健康差异.
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