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Updated: Jul 26, 2026

Transgenic Rodent Assay for Quantifying Male Germ Cell Mutant Frequency
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有证据表明,在男性生殖系中,致病性FGFR2突变具有选择性优势

Anne Goriely1, Gilean A T McVean, Maria Röjmyr

  • 1Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

Science (New York, N.Y.)
|August 2, 2003
PubMed
概括

人类精子突变随着父亲的年龄增加而增加,但高水平来自罕见事件. 矛盾的是,有害的FGFR2突变可能在产生精子的细胞中受到青.

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