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Updated: Jul 26, 2026

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization
15:22

Nucleoside Triphosphates - From Synthesis to Biochemical Characterization

Published on: April 3, 2014

非自然核基稳定性和聚合酶识别的决定因素

Allison A Henry1, Chengzhi Yu, Floyd E Romesberg

  • 1Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California, 92037, USA.

Journal of the American Chemical Society
|August 9, 2003
PubMed
概括

研究人员合成了六个新的非自然核基,以探索它们的DNA配对稳定性和复制效率. 异原子替代影响了稳定性和复制性,特别是在与天然基不匹配的情况下,有助于设计新的DNA基对.

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