微粒体的形状变化和内部分离是由三合一块共聚合物表面活性剂的化学修饰引起的
Zhilian Zhou1, Zhibo Li, Yu Ren
1Department of Chemical Engineering and Materials Science, University of Minnesota, Minneapolis, Minnesota 55455-0431, USA.
Journal of the American Chemical Society
|August 21, 2003
概括
我们从两种两性ABCtriblock共聚合物中表征了. 一个共聚合物的化诱导了内部分离和形圆形状,不像原始共聚合物的球状粒.
科学领域:
- 聚合物化学 聚合物化学
- 材料科学 材料科学 材料科学
- 超分子化学 超分子化学
背景情况:
- 两性ABCtriblock共聚合物在溶液中自组装成微粒.
- 了解块共聚合物自我组装对于设计先进材料至关重要.
研究的目的:
- 为了描述由两个非离子ABCtriblock共聚合物形成的状结构.
- 调查选择性化对细胞形态学的影响.
主要方法:
- 聚乙烯氧化物-b-聚乙烯-b-1,2-聚乙烯 (PEO-b-PS-b-PB) 和其化模拟物的合成和表征.
- 散射技术包括光,中子和X射线散射.
- 传输电子显微镜 (TEM) 成像.
主要成果:
- 非化共聚合物 (OSB) 形成了球形,其核心是均的聚烯-聚丁烯.
- 选择性化聚丁块产生了一个新的共聚合物 (OSF),其内核为F,中间为S.
- 化诱导了从球形转变为形圆形小粒的形状转变.
结论:
- 选择性化显著改变了小细胞形态,因为区块不相容.
- 该研究表明,通过共聚合物修饰,可以控制小形状和内部结构.
- 这些发现与纳米技术和药物输送中的应用有关.
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