基因机制和约束,决定了多类的相关特征的演变
Nicolas Gompel1, Sean B Carroll
1Howard Hughes Medical Institute and Laboratory of Molecular Biology, University of Wisconsin, 1525 Linden Drive, Madison, Wisconsin 53706, USA.
Nature
|August 22, 2003
概括
果颜色和三胞体模式的进化变化通常涉及同一个基因,Bric-à-brac2 (Bab2). 这个基因,这个基因.
科学领域:
- 进化生物学是进化生物学.
- 遗传学 是一个遗传学.
- 发育生物学是发展生物学.
背景情况:
- 物种之间的形态特征多样性提出了关于共享遗传机制和融合进化的问题.
- 果色素化提供了一个模型系统,由于不同的模式,类似特征的独立进化,和识别的调节基因.
研究的目的:
- 调查果的形态特征的进化多样化和融合进化是否涉及同一基因的变化.
- 为了检查Bric-à-brac2 (Bab2) 基因在Drosophilinae物种的腹部色素和三角体模式的演变中的作用.
主要方法:
- 在13个Drosophilinae物种中对腹部色素和三角体模式进行比较分析.
- 检查与观察到的形态模式相关的Bric-à-brac2 (Bab2) 基因表达.
主要成果:
- 在Bab2表达的修改经常与多样化和独立演变的色素和三角体模式相关联.
- 在一些物种中,Bab2表达变化与保存的三体模式有关,这表明它可以绕过新的色素进化.
结论:
- Bric-à-brac2 (Bab2) 位点在果形态特征的多样化和趋同方面发挥着重要作用.
- 对相关性特征的进化约束可能导致绕过关键调节基因,如Bab2,以形成新型模式.
相关概念视频
Mutation, Gene Flow, and Genetic Drift
In a population that is not at Hardy-Weinberg equilibrium, the frequency of alleles changes over time. Therefore, any deviations from the five conditions of Hardy-Weinberg equilibrium can alter the genetic variation of a given population. Conditions that change the genetic variability of a population include mutations, natural selection, non-random mating, gene flow, and genetic drift (small population size).
Position-effect Variegation
In 1928, a German botanist Emil Heitz observed the moss nuclei with a DNA binding dye. He observed that while some chromatin regions decondense and spread out in the interphase nucleus, others do not. He termed them euchromatin and heterochromatin, respectively. He proposed that the heterochromatin regions reflect a functionally inactive state of the genome. It was later confirmed that heterochromatin is transcriptionally repressed, and euchromatin is transcriptionally active chromatin.
Background and Environment Affect Phenotype
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
The Ratio of X Chromosome to Autosomes
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Evolution of New Traits in Microbes
Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...


