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单分子测量蛋白质折叠动力学

Everett A Lipman1, Benjamin Schuler, Olgica Bakajin

  • 1Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, Building 5, Room 104, National Institutes of Health, Bethesda, MD 20892-0520, USA.

Science (New York, N.Y.)
|August 30, 2003
PubMed
概括

研究人员开发了一种新的技术来研究远离平衡的单个分子. 这种方法追踪蛋白质折叠的动态,并揭示隐藏的子群体,提供了超越传统平衡实验的见解.

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Mechanical Protein Functions01:58

Mechanical Protein Functions

Proteins perform many mechanical functions in a cell. These proteins can be classified into two general categories- proteins that generate mechanical forces and proteins that are subjected to mechanical forces. Proteins providing mechanical support to the structure of the cell, such as keratin, are subjected to mechanical force, whereas proteins involved in cell movement and transport of molecules across cell membranes, such as an ion pump, are examples of generating mechanical force.