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Updated: Jul 18, 2026

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

根据CueR的金属离子选择性和zeptomolar灵敏性的分子基础

Anita Changela1, Kui Chen, Yi Xue

  • 1Department of Biochemistry, Molecular Biology, and Cell Biology, Northwestern University, 2205Tech Drive, Evanston, IL 60208, USA.

Science (New York, N.Y.)
|September 6, 2003
PubMed
概括

大肠杆菌的铜外流基因受到CueR的调节,这是一种对铜离子 (Cu+) 具有zeptomolar敏感性的转录激活剂. 结构分析揭示了一个不寻常的金属结合部位,可以实现超敏感的基因切换.

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