蜂网络是人类空间导航的基础
Arne D Ekstrom1, Michael J Kahana, Jeremy B Caplan
1Volen Center for Complex Systems, Brandeis University, Waltham, Massachusetts 02454, USA.
Nature
|September 12, 2003
概括
人类的导航涉及不同的脑细胞:海马细胞绘制空间地图,而副海马细胞识别地标景观. 这揭示了空间定向的双重神经代码.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 空间导航 空间导航
背景情况:
- 动物在海马环境中放置细胞,但人类的导航机制仍在争论中.
- 人类海马和副海马区域参与导航,但也对视觉刺激做出反应.
- 目前尚不清楚人类的空间编码是否反映了动物的位置细胞,还是依赖于视觉机制.
研究的目的:
- 研究人类空间导航的神经基础.
- 为了确定人类导航是否使用特定位置的单元和/或特定视图的单元.
- 在人类导航中区分空间绘图和视觉处理.
主要方法:
- 来自人类中间叶和前叶的317个神经元的直接神经记录.
- 实验对象在一个虚拟的城市环境中进行了导航.
- 对与空间位置,视图和导航目标有关的神经元发射模式的分析.
主要成果:
- 确定了两种不同的神经元群体,涉及到人类的空间导航.
- 海马神经元主要向特定的空间位置 (位置细胞) 发射.
- 副海马神经元对地标的特定视图 (视图细胞) 作出反应.
- 额叶和叶神经元编码了导航目标,并结合了关于位置,目标和视图的信息.
结论:
- 人类的空间导航采用双重的神经代码:海马的位置细胞和副海马的视图细胞.
- 这一发现为人类动物位置编码的同类提供了证据.
- 这些发现表明,在人类导航中,空间,视觉和目标导向信息的复杂整合.
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