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A Legendre¹, J Losay, A Touchot-Koné

¹Centre Chirurgical Marie-Lannelongue, 133 avenue de la Resistance, 92350 Le Plessis-Robinson, France. alegendre@ccml.com

|September 13, 2003

概括

大动脉转移的动脉切换手术 (ASO) 后的冠状动脉事件很常见,特别是在早期,并且可能是致命的. 建议进行冠状动脉血管学诊断,因为非侵入性测试的灵敏度不足.

科学领域:

心血管外科心血管外科
儿童心脏病学儿童心脏病学
遗传性心脏病是一种先天性心脏病.

背景情况:

动脉切换操作 (ASO) 是大动脉转移的一个关键程序.
冠状动脉转移是ASO的一个关键组成部分.
后ASO冠状动脉事件带来了显著的风险.

研究的目的:

为了确定ASO后冠状动脉事件的发病率和风险因素.
评估在ASO后诊断冠状动脉阻塞时的非侵入性测试的灵敏度.

主要方法:

在1982年至2001年期间接受ASO的1304名患者的回顾性分析.
对1198名医院幸存者的随访,平均为59个月.
在324名患者的冠状动脉血管学;在子集的非侵入性测试 (心电图,心声图,跑步机,光学图).

主要成果:

冠状动作发生在7.2%的患者中,两种模式的发病率 (早期和晚期).
风险因素包括特定的冠状动脉模式 (B/C型) 和手术事件.
冠状动脉扫描显示,6.8%的患者有病变.
结合的非侵入性测试实现了75%的诊断灵敏度.

结论:

冠状动脉事件是ASO后的重要并非罕见的并发症,影响生存率.
非侵入性诊断测试缺乏足够的灵敏度来检测延迟冠状动脉狭窄.
冠状动脉血管造影对于准确的诊断和管理至关重要.

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