在患有慢性缺血性左心室功能障碍的患者中,运动诱导的 mitra 反变化的预后重要性
Patrizio Lancellotti1, Pierre Troisfontaines, Anne-Christine Toussaint
1Department of Cardiology, University Hospital of Liège, B-4000 Liege, Belgium.
Circulation
|September 17, 2003
概括
在心脏病发作后的患者中,评估运动诱导的额头上 (MR) 度的变化,提供了关键的预后信息. 运动期间MR的显著增加识别了需要密切监测的高风险个体.
科学领域:
- 心脏病学 心脏病学
- 心血管生理学心血管生理学
- 心声回声扫描 (Echocardiography) 是一种心声回声扫描.
背景情况:
- 心肌梗塞后的死亡风险与 mitrale regurgitation (MR) 的严重程度相关.
- 缺血性MR是一种动态状况,在运动期间可能被评估.
- 运动诱导的MR变化的预后值仍然未确定.
研究的目的:
- 为了确定运动引起的MR程度变化的定量评估是否为患有缺血性MR和左心室功能障碍的患者提供预后信息.
主要方法:
- 对98名患有慢性缺血左心室功能障碍和至少轻度MR的患者进行前性研究.
- 在休息和运动期间量化测量MR反体积和有效反体孔 (ERO).
- 随访时间为19个月,手术患者被审查.
主要成果:
- 心脏死亡的独立预测因素包括运动诱导的ERO增加 (>13毫米2),休息ERO (>20毫米2),以及较短的 mitra减速时间.
- 运动诱导的MR显著增加的患者死亡率更高.
- 在运动期间MR降低的患者中,没有发生心脏病死亡.
结论:
- 运动诱导的MR变化的定量评估在缺血性MR患者中提供了独立的预后价值.
- 显著的运动诱导的MR增加确定了患有不良结果高风险的患者.
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