麦产品和降脂剂. 麦产品和降脂剂. 一个元分析
C M Ripsin1, J M Keenan, D R Jacobs
1Department of Family Practice and Community Health, University of Minnesota, Minneapolis 55414.
JAMA
|July 4, 1992
概括
吃麦可以适度地降低血液中总胆固醇. 这种效应在初始胆固醇水平较高的个体和每天至少摄入3g可溶性纤维时更为明显.
科学领域:
- 营养科学 营养科学
- 心血管健康 心血管健康
- 饮食干预 饮食干预
背景情况:
- 血中总胆固醇升高是心血管疾病的重要危险因素.
- 饮食修改是胆固醇管理的基石.
- 麦因其潜在的健康益处而闻名,包括降胆固醇的特性.
研究的目的:
- 为了评估食用麦对血液中总胆固醇水平的影响.
- 为了确定可能改变麦摄入量和降低胆固醇之间的关系的因素.
主要方法:
- 发表和未发表的随机对照试验的系统审查和元分析.
- 纳入标准要求对饮食和体重变化进行正式评估.
- 数据合成使用了DerSimonian和Laird方法来计算总结效应大小.
主要成果:
- 麦的消费导致了血液总胆固醇的适度降低.
- 降低胆固醇的整体效应大小为-0.13 mmol/L.
- 在具有较高基线胆固醇水平 (≥5.9 mmol/L) 和消耗≥3g可溶性纤维的参与者中观察到更大的胆固醇降低.
结论:
- 将麦产品纳入饮食中,可以支持血胆固醇的适度降低.
- 麦的降胆固醇效应受到基线胆固醇水平和可溶性纤维摄入量的影响.
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