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Updated: Jul 18, 2026

Wild-type Blocking PCR Combined with Direct Sequencing as a Highly Sensitive Method for Detection of Low-Frequency Somatic Mutations
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通过威尔姆斯瘤wt1基因转录的替代拼接来调节DNA结合特异性

W A Bickmore1, K Oghene, M H Little

  • 1Medical Research Council Human Genetics Unit, Western General Hospital, Edinburgh, Scotland.

Science (New York, N.Y.)
|July 10, 1992
PubMed
概括

wt1基因的替代拼接产生了不同的DNA结合蛋白. 这种Wt1蛋白结合特异性的差异影响了生理目标,突出了替代拼接的可能性.

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