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Updated: Jul 18, 2026

Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Published on: June 15, 2017

Raf-1 激活了 MAP 激酶-激酶

J M Kyriakis1, H App, X F Zhang

  • 1Diabetes Unit, Medical Services, Massachusetts General Hospital, Charlestown 02129.

Nature
|July 30, 1992
PubMed
概括

这种c-raf-1原核子基因产物是一种血清蛋白/氨酸蛋白激酶,直接激活MAP激酶-激酶 (MAPK-K). 这一发现确定MAPK-K是c-Raf-1的第一个生理基质,澄清了细胞信号通路中的关键步骤.

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