在儿童病房爆发了帕尔沃病毒B19疫情
1Division of Communicable Diseases, Royal Free Hospital and School of Medicine, London, UK.
Lancet (London, England)
|January 11, 1992
概括
帕尔沃病毒B19疫情对脆弱人群构成风险. 在医院爆发期间,采取了感染控制措施,但它们在限制传播方面的有效性仍然不确定.
科学领域:
- 病毒学 病毒学
- 传染性疾病 传染性疾病
- 医院流行病学 医院流行病学
背景情况:
- 帕尔沃病毒B19感染对孕妇,血液溶解性贫血患者和免疫受损者构成重大风险.
- 管理医院疫情需要平衡患者保护与维持基本医疗服务.
研究的目的:
- 为了调查帕尔沃病毒B19在儿科病房的爆发.
- 评估疫情期间实施的感染控制措施.
主要方法:
- 对58名医院工作人员进行帕尔沃病毒B19标志物 (血清IgM和病毒性血清) 的查.
- 评估易感人员和免疫受损患者感染的发展情况.
- 实施隔离,免疫球蛋白治疗和病房限制.
主要成果:
- 6名易受感染的男性工作人员中有4人,24名易受感染的女性工作人员中有6人感染 (p=0.05).
- 11名成年感染者中有1名和12名免疫功能低下患者中有2名仍然没有症状.
- 实施的措施与感染传播限制之间没有明确的相关性.
结论:
- 帕尔沃病毒B19可以在医院环境中无症状传播.
- 在此次疫情期间,无法确定特定感染控制干预措施的有效性.
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