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相关概念视频

Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...

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Width of excision margins after breast conserving surgery for invasive breast cancer and distant recurrence and survival.

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相关实验视频

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Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay
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Accurate and Simple Measurement of the Pro-inflammatory Cytokine IL-1β using a Whole Blood Stimulation Assay

Published on: March 2, 2011

甲状腺前激素相关蛋白质的测定在过血症的调查中的作用

W A Ratcliffe1, A C Hutchesson, N J Bundred

  • 1Wolfson Research Laboratories, Queen Elizabeth Medical Centre, Birmingham, UK.

Lancet (London, England)
|January 18, 1992
PubMed
概括

甲状腺激素相关蛋白 (PTHrP) 在癌症中引起高血症. 测量PTHrP和副甲状腺激素 (PTH) 有助于诊断高水平的原因,改善患者管理.

科学领域:

  • 内分泌学 在内分泌学.
  • 在瘤学瘤学.
  • 临床生物化学 临床生物化学

背景情况:

  • 过热血是恶性瘤中常见的,通常由甲状腺激素相关蛋白 (PTHrP) 介导.
  • 从临床上来说,区分恶性瘤相关的高血症和原发性甲状腺功能障碍症是非常重要的.

研究的目的:

  • 研究PTHrP和副甲状腺激素 (PTH) 在高血症中的作用.
  • 评估PTHrP和PTH测定在常规临床实践中的诊断效用.

主要方法:

  • 使用敏感的免疫放射测定测量血PTHrP和血清PTH度.
  • 分析了121名连续的高血症患者 (血清 > 2.65 mmol/l).

主要成果:

  • 超血是由于原发性偏甲状腺功能障碍症 (52%) 或恶性瘤 (49%) 引起的.
  • 在88%的实体瘤患者中发现可检测的PTHrP;在92%的原发性副甲状腺症患者中没有检测到.
  • 联合PTH和PTHrP测量改变了7%的患者的诊断.

结论:

  • 提供了瘤衍生PTHrP作为超血的幽默调解物的直接证据.
  • 建议结合PTHrP和PTH测定,以便在临床环境中有效地调查高血症.

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Extracellular Vesicle Tissue Factor Activity Assay

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