在患有乳腺癌的女性中逆转大脑不对称
T A Sandson1, P Y Wen, M LeMay
1Department of Neurology, Beth Israel Hospital, Boston, Massachussetts 02215.
Lancet (London, England)
|February 29, 1992
概括
与对照组相比,患有乳腺癌的女性表现出明显更多的逆向大脑不对称模式. 这表明早期的荷尔蒙因素可能会增加乳腺癌的风险.
科学领域:
- 神经科学是一个神经科学.
- 在瘤学瘤学.
- 内分泌学 在内分泌学.
背景情况:
- 非典型的大脑不对称性与各种疾病有关.
- 早期发育期间的荷尔蒙影响对大脑和生殖系统的成熟至关重要.
研究的目的:
- 研究大脑不对称模式与乳腺癌之间的关联.
- 探索早期可能对乳腺癌发展产生荷尔蒙影响.
主要方法:
- 分析了79名患有乳腺癌的女性和97名对照女性的计算机断层扫描 (CT) 扫描.
- 评估了大脑不对称的模式,特别是额头和尾宽度.
- 参与者是右撇子和白人.
主要成果:
- 与对照组相比,患有乳腺癌的女性更频繁地表现出脑部不对称的反向模式.
- 这一差异对于前额 (p < 0.0001) 和后额 (p < 0.0001) 宽度都具有统计学意义.
结论:
- 研究结果表明,非典型的大脑不对称性与乳腺癌之间存在潜在联系.
- 子宫内或早期的荷尔蒙因素可能会使个人在以后的生活中容易患乳腺癌.
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