随机对照试验,研究鱼油补充剂对怀孕持续时间的影响
S F Olsen1, J D Sørensen, N J Secher
1Institute of Epidemiology and Social Medicine, University of Aarhus, Denmark.
Lancet (London, England)
|April 25, 1992
概括
在怀孕的第三个三个月中补充鱼油可能会延长妊娠时间. 这项研究发现,鱼油中的n-3脂肪酸可以延长怀孕,而不会对胎儿生长或分娩产生不良影响.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 围产儿医学 围产儿医学
背景情况:
- 在法罗群岛观察到的高出生体重和长期怀孕表明,来自海洋脂肪的n-3脂肪酸发挥了作用.
- n-3脂肪酸可能会影响前列腺素的产生,影响分娩时间.
研究的目的:
- 研究鱼油补充剂对怀孕时间,出生体重和出生长度的影响.
- 在健康的孕妇中比较鱼油,橄油和没有补充剂.
主要方法:
- 随机对照试验涉及533名30周怀孕的健康丹麦妇女.
- 参与者被分配接受鱼油 (n-3脂肪酸),橄油或没有补充剂.
- 孕期长度,出生体重和出生长度是主要的结果指标.
主要成果:
- 平均怀孕时间在各组之间有显著差异 (p = 0.006),在鱼油组中最长.
- 鱼油补充剂导致怀孕比橄油组长4.0天,出生体重差异为107克.
- 鱼油对孕期长度的影响在基线鱼类摄入量较低的女性中更为明显.
结论:
- 第三个三个月的鱼油补充剂似乎可以延长怀孕.
- 这种延长并没有对胎儿生长或分娩过程产生不利影响.
- 摄入的n-3脂肪酸可能是调节妊娠持续时间的一个因素.
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