素食大豆饮食对脏病综合征高脂血症的影响
G D'Amico1, M G Gentile, G Manna
1Division of Nephrology, San Carlo Hospital, Milan, Italy.
Lancet (London, England)
|May 9, 1992
概括
素食大豆饮食显著降低了脏病患者的高脂血症和蛋白尿症. 在恢复正常饮食后,这些改善恢复到基线,这表明饮食.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 营养科学 营养科学
- 心血管健康 心血管健康
背景情况:
- 病患者经常表现出脂质异常,增加动脉样硬化和病进展的风险.
- 超脂血症是慢性淋巴细胞疾病和持续性蛋白尿症患者的常见并发症.
- 目前正在探索饮食干预措施,以管理脂概况和脏病综合征的脏结果.
研究的目的:
- 研究一种基于大豆的素食饮食在纠正脏病患者中高脂血症的疗效.
- 评估饮食操纵对慢性病患者蛋白尿和脂质异常的影响.
主要方法:
- 一项受控研究涉及20名未经治疗的患有蛋白尿和高脂血症的脏病患者.
- 用素食大豆饮食进行为期8周的干预 (低脂肪,低蛋白,无胆固醇,高纤维,特定脂肪酸特征).
- 随后进行了为期8周的休息期,患者恢复了通常的饮食.
主要成果:
- 在大豆饮食期间观察到总胆固醇,LDL,HDL和阿波利波蛋白A和B的显著降低.
- 血清甘油三水平保持不变.
- 尿路蛋白质分泌显著下降,在洗阶段,值往往会恢复到基线.
结论:
- 素食大豆饮食可以有效地改善脂质样本,并减少脏病患者的蛋白尿症.
- 对蛋白尿的观察到的好处可能与饮食中的蛋白质修改或脂质摄入量变化有关.
- 需要进一步的研究来阐明饮食对功能有利影响背后的具体机制.
相关概念视频
Hormones Regulating Blood Glucose
Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
In addition to accelerating glucose uptake and utilization, insulin has...
In addition to accelerating glucose uptake and utilization, insulin has...
Diabetes Mellitus: Type 2 and Gestational
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...
Diabetes: Management and Pharmacotherapy
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Hypertension IV: Drug Therapy and Lifestyle Modifications
Multiple classes of antihypertensive medications are employed in treating hypertension. The most commonly recommended first-line treatments include:Thiazide Diuretics, such as chlorthalidone, increase sodium and water excretion from the body, reducing blood volume and blood pressure.Angiotensin-converting enzyme inhibitors, like lisinopril, block the conversion of angiotensin I to II, a potent vasoconstrictor lowering blood pressure.Angiotensin II Receptor Blockers (ARBs) prevent angiotensin II...
Type II Diabetes II: Pathophysiology
PathophysiologyType 2 diabetes mellitus (T2DM ) is a chronic metabolic disorder characterized by insulin resistance and progressive pancreatic β-cell dysfunction, leading to impaired glucose homeostasis. It results from interactions among genetic predisposition, environmental factors, and metabolic stressors, such as overnutrition and a sedentary lifestyle.Insulin Resistance and Glucose DysregulationEarly T2DM involves insulin resistance in skeletal muscle, adipose tissue, and the liver.
