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Updated: Jun 19, 2026

Recombineering Homologous Recombination Constructs in Drosophila
14:23

Recombineering Homologous Recombination Constructs in Drosophila

Published on: July 13, 2013

V(D) J重组:破碎的DNA分子与共价密封 (发针) 编码结束在scid小鼠胸细胞中

D B Roth1, J P Menetski, P B Nakajima

  • 1Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892.

Cell
|September 18, 1992
PubMed
概括

严重联合免疫缺陷 (SCID) 鼠标淋巴细胞启动V(D) J重组,但难以连接DNA段. 与正常小鼠不同,SCID胸细胞显示了破损的DNA,其编码末端与发针密封,这表明SCID因子在V(D) J修复中发挥了作用.

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Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae07:55

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