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相关概念视频

Development of the Oral Microbiota01:28

Development of the Oral Microbiota

The establishment of the oral microbiome begins before birth, challenging the long-held belief that the fetal oral cavity is sterile. The presence of oral microbes such as Streptococcus and Fusobacterium in amniotic fluid suggests that microbial exposure may occur in utero, potentially through translocation from the maternal oral or gastrointestinal tract. This early colonization primes the neonatal immune system and sets the stage for subsequent microbial succession. Maternal health,...

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相关实验视频

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Surgical Approach, Challenges, and Resolutions for Uterus Transplantation in Rats
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自发胎儿损失的完整后续检查的重要性,在羊膜切割和胆样本取样后.

J L Halliday1, J Lumley, L J Sheffield

  • 1Murdoch Institute for Research into Birth Defects, Parkville, Victoria, Australia.

Lancet (London, England)
|October 10, 1992
PubMed
概括

与胆样本 (1.2% 早期, 2.9% 总体) 相比,乳液切割的胎儿损失率较低 (0.2% 早期, 1.3% 总体). 操作人员的经验和妊娠年龄会影响胆毛样本取样风险.

科学领域:

  • 产科和妇科 产科和妇科
  • 产前诊断 在产前诊断
  • 生殖医学 生殖医学

背景情况:

  • 乳液切割和胆囊取样本是常见的产前诊断程序.
  • 准确的胎儿损失数据对于知情的产前咨询至关重要.
  • 怀孕后不良后果的妇女在术后的随访中面临挑战.

研究的目的:

  • 为了确定和比较胎儿丧失率的羊切片和胆毛样本采集.
  • 在这些程序中确定影响胎儿损失风险的因素.
  • 为改善产前咨询提供数据.

主要方法:

  • 一项多中心研究跟踪了100%的女性进行了羊切片或胆毛样本采集.
  • 胎儿损失被分类为早期自发 (3周内) 或完全自发.
  • 统计分析包括针对已识别的风险因素的相对风险 (RR) 计算.

主要成果:

  • 早期自发性损失: 0.2% 对于羊膜切割 vs. 1.2% 对于胆毛样本采集.
  • 总自发性损失: 羊膜切开时1.3%,胆膜取样时2.9%.
  • 毛样本采集风险在操作人员缺乏经验时增加 (RR 4.3) 并且在怀孕≥10周时进行时较低 (RR 0.4).

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结论:

  • 与胆样本采集相比,羊膜切割显示胎儿损失率明显较低.
  • 操作人员的经验和妊娠年龄是影响胆毛样本取样结果的关键因素.
  • 综合结果数据表是关于这些程序的产前咨询的宝贵工具.