在慢性心力衰竭中运行氧气
L J Restrick1, S W Davies, L Noone
1Department of Thoracic Medicine, London Chest Hospital, UK.
Lancet (London, England)
|November 14, 1992
概括
在慢性心力衰竭患者中,门诊氧疗没有改善步行距离或减少呼吸困难. 在运动期间不建议这些患者使用当前的氧气瓶.
科学领域:
- 心脏病学 心脏病学
- 肺部医学 肺部医学
- 运动生理学 运动生理学
背景情况:
- 慢性心力衰竭 (CHF) 与运动不耐受有关.
- 健行氧气治疗有时在炼期间使用,但其在慢性心血管疾病患者在步行期间的疗效尚未得到充分证实.
- 在患有心血管衰竭的个体中,氧和度 (SaO2) 在运动期间经常下降.
研究的目的:
- 评估 ambulatory氧疗对慢性心力衰竭患者在步行测试期间运动表现和气体交换的影响.
- 为了确定补充氧气是否会改善SaO2,步行距离,或在次最大和耐力步行期间感知到呼吸困难.
主要方法:
- 12名患有慢性心力衰竭的患者进行了6分钟步行测试和耐力步行.
- 测量包括静脉氧和度 (SaO2) 在休息和运动期间,步行距离和呼吸困难.
- 进行了呼吸环境空气和通过便携式气瓶输送的补充氧气 (2L/分钟和4L/分钟) 的测试.
主要成果:
- 在6分钟的步行过程中,SaO2从休息 (94.4%) 到运动 (90.1%) 的时间显著下降,当呼吸空气时.
- 2升/分钟的补充氧气增加了休息时的SaO2 (93.7%至96.5%),但没有影响运动的SaO2,距离或呼吸困难.
- 在耐力散步期间,4升/分钟的氧气增加了最低的SaO2 (90.4%至93.5%),但没有改善呼吸困难或距离.
结论:
- 使用目前可用的便携式气瓶进行的门诊氧气疗法不会改善运动能力,也不会减少慢性心力衰竭患者在走路时的呼吸困难.
- 这些发现不支持在运动测试期间为患有CHF的患者常规使用门诊氧气.
- 可能需要进一步的研究来探索最佳的氧气输送方法或患者选择在心血管衰竭中进行门诊氧气治疗.
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