在扩张性心肌病症中,双室节奏与短暂的心房延迟的影响
S J Brecker1, H B Xiao, J Sparrow
1Cardiac Department, Royal Brompton National Heart and Lung Hospital, London, UK.
Lancet (London, England)
|November 28, 1992
概括
在扩张性心肌病患者中,双室节奏与短暂的心房延迟有效地减少了反持续时间,改善了心脏输出和运动能力. 这种节奏策略显示了改善症状和功能的治疗潜力.
科学领域:
- 心脏病学 心脏病学
- 生物医学工程 生物医学工程
- 心脏衰竭研究研究
背景情况:
- 扩张性心肌病症可能导致腹腔填充时间缩短,原因是心肌或三回,限制了中风体积.
- 优化心室填充时间对于改善这些患者的心脏功能至关重要.
研究的目的:
- 评估在双室DDD节奏过程中改变心房 (AV) 间隔对心室填充时间和心脏功能的影响.
- 研究扩张性心肌病患者中短 AV 延迟的治疗潜力,这些患者有吐诱导的短填充时间.
主要方法:
- 十二名患有扩张性心肌病症和短心室填充时间的患者接受了临时或永久的DDD节奏.
- 用多普勒回声心脏成像来测量心室填充时间和心脏输出在基线和优化AV延迟时.
- 使用跑步机测试来评估运动能力.
主要成果:
- 缩短AV间隔显著减少了 mitra和三腹排泄的持续时间,增加了左和右心室填充时间.
- 心脏输出增加了1.1升/分钟,运动持续时间增加了104秒,最大氧气消耗增加了2.1毫升/公斤/分钟.
- 在运动高峰时的呼吸困难显著减少,这表明运动耐受性有所改善.
结论:
- 带有短时间的AV延迟的DDD节奏可以有效地缩短反的持续时间并改善心室填充.
- 这种节奏策略提高了心脏输出,运动能力,并在扩大心肌病患者中减少呼吸障碍.
- 短期AV延迟节奏甚至在没有标准心脏起器指示的情况下也可能提供治疗益处.
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