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相关概念视频

Blood Types02:20

Blood Types

Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Disorders of Erythrocytes01:27

Disorders of Erythrocytes

Disorders of erythrocytes, or red blood cells (RBCs), include a range of conditions affecting their number, shape, or function.
Erythrocyte disorders can be broadly categorized into two main types: anemic and polycythemic conditions.
A low oxygen-carrying capacity of the blood due to the loss, lower production, or destruction of erythrocytes is termed anemia. Hemorrhagic anemia, for example, occurs when bleeding from an external wound or internal ulcer reduces erythrocyte counts.
On the other...
Blood Typing01:10

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...

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相关实验视频

Updated: Jun 29, 2026

Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis
11:50

Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis

Published on: April 10, 2012

人类乙血症中的载体状态.

E T NISHIMURA, H B HAMILTON, T Y KOBARA

    Science (New York, N.Y.)
    |August 7, 1959
    PubMed
    概括

    阿卡塔拉血症是一种罕见的遗传性疾病,在生物化学上定义为受影响个体缺少血液中催化酶活性. 异胞体表现出中间活动水平,使其与正常个体区分开来,并证实了载体地位.

    科学领域:

    • 生物化学 生物化学
    • 遗传学 是一个遗传学.
    • 人体生理学 人体生理学

    背景情况:

    • 甲血症是一种罕见的遗传代谢障碍.
    • 血液中的catalase酶活性对细胞保护至关重要.
    • 了解载体状态对于遗传咨询和疾病管理至关重要.

    研究的目的:

    • 为了生化地定义亚卡塔拉血症的异合体载体状态.
    • 根据血液的催化酶活性来区分受影响的同位素,异位素和正常个体.
    • 为了研究遗传遗传模式,包括血缘关系,在acatalasemia.

    主要方法:

    • 生物化学试验测量血液中催化酶活性.
    • 在受影响的个体和对照中分析酶活性水平.
    • 血统分析可以追踪遗传模式.

    主要成果:

    • 受影响的个体 (同位素) 没有可检测的血液催化酶活性.
    • 异构体表现出中间的血液催化酶活性,与正常个体明显不同.
    • 血统数据显示,受影响家庭中血缘婚姻的频率很高.

    结论:

    关键词:
    卡塔拉斯/在血液中

    更多相关视频

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    Real-time Cytotoxicity Assays in Human Whole Blood

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    Characterizing Mutational Load and Clonal Composition of Human Blood
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    Characterizing Mutational Load and Clonal Composition of Human Blood

    Published on: July 11, 2019

    相关实验视频

    Last Updated: Jun 29, 2026

    Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis
    11:50

    Ex vivo Mimicry of Normal and Abnormal Human Hematopoiesis

    Published on: April 10, 2012

    Real-time Cytotoxicity Assays in Human Whole Blood
    08:27

    Real-time Cytotoxicity Assays in Human Whole Blood

    Published on: November 7, 2014

    Characterizing Mutational Load and Clonal Composition of Human Blood
    07:58

    Characterizing Mutational Load and Clonal Composition of Human Blood

    Published on: July 11, 2019

    • 通过对血液中催化酶活性进行生化测量,可以可靠地确定乙酶血症的异合体载体状态.
    • 阿卡塔拉血症遵循自体逆向遗传模式,血缘关系增加了受影响的同胞细胞的发生率.
    • 生物化学表型化对于准确的诊断和基因咨询在acatalasemia是必不可少的.