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Updated: Jul 6, 2026

Mutagenesis and Analysis of Genetic Mutations in the GC-rich KISS1 Receptor Sequence Identified in Humans with Reproductive Disorders
12:49

Mutagenesis and Analysis of Genetic Mutations in the GC-rich KISS1 Receptor Sequence Identified in Humans with Reproductive Disorders

Published on: September 4, 2011

分子克隆的介质素-1β转化酶的克隆

D P Cerretti1, C J Kozlosky, B Mosley

  • 1Immunex Corporation, Seattle, WA 98101.

Science (New York, N.Y.)
|April 3, 1992
PubMed
概括

研究人员克隆了一种蛋白质酶,该蛋白质酶可以将Interleukin-1β (IL-1β) 转化为其活性形式. 这种酶是这种酶.

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The TGF-β signaling pathway regulates cell growth, differentiation, adhesion, motility, and development. TGF-β ligands that induce TGF-β signaling are synthesized in their latent form. Several proteases or cell surface receptors such as integrins act upon the latent form, releasing the active ligand. There are three types of mammalian TGF-βs: (TGF-β1, TGF-β2, and TGF-β3) that bind as homodimers or heterodimers to TGF-β receptors. The TGF-β receptors are of three kinds RI, RII, and RIII. The RI...