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Updated: Aug 1, 2026

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
08:47

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

Published on: May 8, 2016

CD8+ T 细胞在小鼠实验性过敏脑膜炎中的作用

H Jiang1, S I Zhang, B Pernis

  • 1Department of Microbiology, College of Physicians and Surgeons, Columbia University, New York, NY 10032.

Science (New York, N.Y.)
|May 22, 1992
PubMed
概括

CD8+ T 细胞对于对随后的实验性过敏性脑膜炎 (EAE) 复发产生抗性至关重要. 然而,在这种动物模型中,它们对于从最初的EAE事件中恢复来说并不必不可少.

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Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo10:50

Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo

Published on: March 26, 2019

相关概念视频

T Cell Types and Functions01:24

T Cell Types and Functions

When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...