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相关概念视频

The Resting Membrane Potential01:21

The Resting Membrane Potential

Overview
Fixed Action Patterns01:06

Fixed Action Patterns

A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
Osmoregulation in Fishes02:32

Osmoregulation in Fishes

When cells are placed in a hypotonic (low-salt) fluid, they can swell and burst. Meanwhile, cells in a hypertonic solution—with a higher salt concentration—can shrivel and die. How do fish cells avoid these gruesome fates in hypotonic freshwater or hypertonic seawater environments?
Resting Membrane Potential01:24

Resting Membrane Potential

The relative difference in electrical charge, or voltage, between the inside and the outside of a cell membrane, is called the membrane potential. It is generated by differences in permeability of the membrane to various ions and the concentrations of these ions across the membrane.
The Inside of a Neuron is More Negative
The membrane potential of a cell can be measured by inserting a microelectrode into a cell and comparing the charge to a reference electrode in the extracellular fluid. The...
G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory organs,...
Transduction01:16

Transduction

Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome are...

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相关实验视频

Updated: Jul 15, 2026

A Time Differential Staining Technique Coupled with Full Bilateral Gill Denervation to Study Ionocytes in Fish
11:24

A Time Differential Staining Technique Coupled with Full Bilateral Gill Denervation to Study Ionocytes in Fish

Published on: March 19, 2015

从一个teleost的内刺激的正负增强.

E S BOYD, L C GARDNER

    Science (New York, N.Y.)
    |May 18, 1962
    PubMed
    概括

    研究人员在金鱼中发现了不同的大脑区域,这些区域是积极或负面的奖励. 这些发现来自涉及大脑刺激和操作行为测试的实验.

    科学领域:

    • 神经科学是一个神经科学.
    • 动物行为 动物行为

    背景情况:

    • 大脑的奖励系统对于理解动机和行为至关重要.
    • 识别特定的奖励和厌恶大脑区域是理解神经电路的关键.

    研究的目的:

    • 为了调查金鱼中积极和负面奖励的大脑区域的存在.
    • 在脊椎动物模型中绘制与奖励和厌恶相关的大脑区域的地图.

    主要方法:

    • 在金鱼中利用直接的电脑刺激,将金鱼置于水箱中.
    • 使用自由操作者行为测试来评估对刺激的反应.
    • 相关的动物的位置在坦克与大脑刺激的交付.

    主要成果:

    • 证明存在积极奖励 (愉快) 和负面奖励 (厌恶) 的大脑区域.
    • 金鱼积极寻找或避免与大脑刺激相关的特定位置.
    • 行为反应表明奖励和厌恶的不同神经基质.

    结论:

    • 金鱼的大脑拥有可识别的区域,可以调解正负增强.
    • 这些发现有助于理解脊椎动物的奖励回路.
    • 这项研究验证了使用行为和刺激范式来绘制大脑奖励系统的有效性.
    关键词:
    行为/生理学大脑/生理学鱼类/生理学

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    Last Updated: Jul 15, 2026

    A Time Differential Staining Technique Coupled with Full Bilateral Gill Denervation to Study Ionocytes in Fish
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